Higher Tooth Pain Predicts Significantly Lower Guiltiness for Population
Contents

Variables

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Tooth Pain 479
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Guiltiness 2319

Categories

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Symptoms 13336
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Emotions 2028

Actions

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Your Data

Tags

Medium Confidence
Strong Effect Size
Negative Relationship
Population Study
cause image gauge image effect image
Participants reported a 17.2% average decrease in Guiltiness following above average Tooth Pain.
Abstract

Abstract

Guiltiness was generally 7.4% lower than average after 1.8 out of 5 of Tooth Pain per 7 days.

Aggregated data from 1 study participants suggests with a MEDIUM degree of confidence (p=0.0261, 95% CI -0.84 to -0.608) that Tooth Pain has a strongly negative predictive relationship (R=-0.724) with Guiltiness.

The highest quartile of Guiltiness measurements were observed following an average 1.75 out of 5 Tooth Pain.

The lowest quartile of Guiltiness measurements were observed following an average 1.78 out of 5 of Tooth Pain.

After an onset delay of 0 seconds, Guiltiness is typically 3% lower than average over the 7 days following around 1.78 out of 5 Tooth Pain.

Objective

Objective

The objective of this study is to determine the nature of the relationship (if any) between Tooth Pain and Guiltiness. Additionally, we attempt to determine the Tooth Pain values most likely to produce optimal Guiltiness values.
Participant Instructions

Participant Instructions

Manual Recording Option

A Create a reminder for Tooth Pain here and record it daily by enabling notifications or using A the reminder inbox here .


Manual Recording Option

A Create a reminder for Guiltiness here and record it daily by enabling notifications or using A the reminder inbox here .

Design

Design

This study is based on data donated by 1 participants. Thus, the study design is equivalent to the aggregation of 1 separate n=1 observational natural experiments.

Data Analysis

Data Analysis

Tooth Pain Pre-Processing

Tooth Pain measurement values below 1 out of 5 were assumed erroneous and removed. Tooth Pain measurement values above 5 out of 5 were assumed erroneous and removed. No missing data filling value was defined for Tooth Pain so any gaps in data were just not analyzed instead of assuming zero values for those times.

Guiltiness Pre-Processing

Guiltiness measurement values below 1 out of 5 were assumed erroneous and removed. Guiltiness measurement values above 5 out of 5 were assumed erroneous and removed. No missing data filling value was defined for Guiltiness so any gaps in data were just not analyzed instead of assuming zero values for those times.

Predictive Analytics

It was assumed that 0 seconds would pass before a change in Tooth Pain would produce an observable change in Guiltiness.

It was assumed that Tooth Pain could produce an observable change in Guiltiness for as much as 7 days after the stimulus event.

Statistical Significance

Statistical Significance

Using a two-tailed t-test with alpha = 0.05, it was determined that the change in Guiltiness is statistically significant at 95% confidence interval.

After treatment, a 17.2% decrease (-0.164 out of 5) from the mean baseline 2.21 out of 5 was observed. The relative standard deviation at baseline was 36.1%. The observed change was 0.20614 times the standard deviation.

A common rule of thumb considers a change greater than twice the baseline standard deviation on two separate pre-post experiments may be considered significant. This occurrence would have only a 5% likelihood of resulting from random fluctuation (a p-value < 0.05).

Data Sources

Data Sources

Tooth Pain data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Guiltiness data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Limitations

Limitations

As with any human experiment, it was impossible to control for all potentially confounding variables. Correlation does not necessarily imply causation. We can never know for sure if one factor is definitely the cause of an outcome. However, lack of correlation definitely implies the lack of a causal relationship. Hence, we can with great confidence rule out non-existent relationships. For instance, if we discover no relationship between mood and an antidepressant this information is just as or even more valuable than the discovery that there is a relationship.

We can also take advantage of several characteristics of time series data from many subjects to infer the likelihood of a causal relationship if we do find a correlational relationship. The criteria for causation are a group of minimal conditions necessary to provide adequate evidence of a causal relationship between an incidence and a possible consequence.

Criteria For Causal Inference

Strength (A.K.A. Effect Size)

A small association does not mean that there is not a causal effect, though the larger the association, the more likely that it is causal. There is a strongly negative (R = -0.724) relationship between Tooth Pain and Guiltiness.

Consistency (A.K.A. Reproducibility)

Consistent findings observed by different persons in different places with different samples strengthens the likelihood of an effect. Furthermore, in accordance with the law of large numbers (LLN), the predictive power and accuracy of these results will continually grow over time. 492 paired data points were used in this analysis. Assuming that the relationship is merely coincidental, as the participant independently modifies their Tooth Pain values, the observed strength of the relationship will decline until it is below the threshold of significance. To it another way, in the case that we do find a spurious correlation, suggesting that banana intake improves mood for instance, one will likely increase their banana intake. Due to the fact that this correlation is spurious, it is unlikely that you will see a continued and persistent corresponding increase in mood. So over time, the spurious correlation will naturally dissipate.

Specificity

Causation is likely if a very specific population at a specific site and disease with no other likely explanation. The more specific an association between a factor and an effect is, the bigger the probability of a causal relationship.

Temporality

The effect has to occur after the cause (and if there is an expected delay between the cause and expected effect, then the effect must occur after that delay). The confidence in a causal relationship is bolstered by the fact that time-precedence was taken into account in all calculations.

Biological Gradient

Greater exposure should generally lead to greater incidence of the effect. However, in some cases, the mere presence of the factor can trigger the effect. In other cases, an inverse proportion is observed: greater exposure leads to lower incidence.

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel.

Based on our responses so far,

0 humans feel that there is a plausible mechanism of action for a relationship between Tooth Pain and Guiltiness.

0 humans feel that any relationship observed between Tooth Pain and Guiltiness is coincidental.

Coherence

Coherence between epidemiological and laboratory findings increases the likelihood of an effect. It will be very enlightening to aggregate this data with the data from other participants with similar genetic, diseasomic, environmentomic, and demographic profiles.

Experiment

All of human life can be considered a natural experiment. Occasionally, it is possible to appeal to experimental evidence.

Analogy

The effect of similar factors may be considered.

Plausibility

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel. Based on our responses so far, 0 humans feel that there is a plausible mechanism of action and 0 feel that any relationship observed between Tooth Pain and Guiltiness is coincidental.

Relationship Statistics

Property Value
Cause Variable Name Tooth Pain
Effect Variable Name Guiltiness
Sinn Predictive Coefficient 0.068897707163867
Confidence Level MEDIUM
Confidence Interval 0.11573
Forward Pearson Predictive Coefficient -0.724
Critical T Value 1.646
Average Tooth Pain Over Previous 7 days Before ABOVE Average Guiltiness 1.75 out of 5
Average Tooth Pain Over Previous 7 days Before BELOW Average Guiltiness 1.78 out of 5
Duration of Action 7 days
Effect Size strongly negative
Number of Paired Measurements 492
Optimal Pearson Product 0.0043746661642764
P Value 0.026071
Statistical Significance 0.9964
Strength of Relationship 0.11573
Study Type population
Analysis Performed At 2021-08-30
Number of Participants 1

Tooth Pain Info

Property Value
Variable Name Tooth Pain
Aggregation Method MEAN
Analysis Performed At 2021-06-16
Duration of Action 24 hours
Kurtosis 2.5523081373523
Maximum Allowed Value 5 out of 5
Mean 2.201325 out of 5
Median 2 out of 5
Minimum Allowed Value 1 out of 5
Number of Aggregate Predictors 419
Number of Aggregate Outcomes 60
Number of Measurements 861
Number of Measurements (including those generated by tagged, joined, or child variables) 861
Public true
Onset Delay 0 seconds
Standard Deviation 0.92925014061285
Unit 1 to 5 Rating
User Variables 4
UPC 047701003527
Variable Category Symptoms
Variable ID 90664
Variance 0.89735267358936

Guiltiness Info

Property Value
Variable Name Guiltiness
Aggregation Method MEAN
Analysis Performed At 2022-09-29
Duration of Action 24 hours
Kurtosis 2.2615389805518
Maximum Allowed Value 5 out of 5
Mean 2.365934400949 out of 5
Median 2.2960569395018 out of 5
Minimum Allowed Value 1 out of 5
Number of Aggregate Predictors 2056
Number of Aggregate Outcomes 263
Number of Measurements 31621
Number of Measurements (including those generated by tagged, joined, or child variables) 31621
Public true
Onset Delay 0 seconds
Standard Deviation 0.5743531754414
Unit 1 to 5 Rating
User Variables 1787
UPC 0
Variable Category Emotions
Variable ID 1335
Variance 0.72121328198661

Principal Investigator

Cite This Study

APA Format
Sinn, M. P. (2026). Higher Tooth Pain Predicts Significantly Lower Guiltiness for Population. The Journal of Citizen Science. https://studies.crowdsourcingcures.org/study/cause-90664-effect-1335-population-study
BibTeX
@misc{sinn_cause_90664_effect_1335_population_study_2026,
  author = {Sinn, Mike P.},
  title = {Higher Tooth Pain Predicts Significantly Lower Guiltiness for Population},
  year = {2026},
  publisher = {The Journal of Citizen Science},
  url = {https://studies.crowdsourcingcures.org/study/cause-90664-effect-1335-population-study},
  note = {Accessed: January 3, 2026}
}
Chicago/Turabian
Sinn, Mike P. "Higher Tooth Pain Predicts Significantly Lower Guiltiness for Population." The Journal of Citizen Science. Accessed January 3, 2026. https://studies.crowdsourcingcures.org/study/cause-90664-effect-1335-population-study.