Higher Abdominal Cramps Predicts Very Slightly Higher Loneliness for Population
Contents
Mike Sinn
PRINCIPAL INVESTIGATOR
Mike Sinn

Variables

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Abdominal Cramps 99
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Loneliness 604

Categories

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Symptoms 13336
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Emotions 2028

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Tags

Low Confidence
Very Weak Effect Size
Positive Relationship
Population Study
cause image gauge image effect image
Participants reported a 1.5% average increase in Loneliness following above average Abdominal Cramps.
Abstract

Abstract

Loneliness was generally 2.85% lower than average after 1.94 out of 5 of Abdominal Cramps per 7 days.

Aggregated data from 2 study participants suggests with a LOW degree of confidence (p=0.379, 95% CI -0.477 to 0.605) that Abdominal Cramps has a very weakly positive predictive relationship (R=0.0639) with Loneliness.

The highest quartile of Loneliness measurements were observed following an average 2 out of 5 Abdominal Cramps.

The lowest quartile of Loneliness measurements were observed following an average 1.89 out of 5 of Abdominal Cramps.

After an onset delay of 0 seconds, Loneliness is typically 1% higher than average over the 7 days following around 1.89 out of 5 Abdominal Cramps.

Objective

Objective

The objective of this study is to determine the nature of the relationship (if any) between Abdominal Cramps and Loneliness. Additionally, we attempt to determine the Abdominal Cramps values most likely to produce optimal Loneliness values.
Participant Instructions

Participant Instructions

Manual Recording Option

A Create a reminder for Abdominal Cramps here and record it daily by enabling notifications or using A the reminder inbox here .


Manual Recording Option

A Create a reminder for Loneliness here and record it daily by enabling notifications or using A the reminder inbox here .

Design

Design

This study is based on data donated by 2 participants. Thus, the study design is equivalent to the aggregation of 2 separate n=1 observational natural experiments.

Data Analysis

Data Analysis

Abdominal Cramps Pre-Processing

Abdominal Cramps measurement values below 1 out of 5 were assumed erroneous and removed. Abdominal Cramps measurement values above 5 out of 5 were assumed erroneous and removed. No missing data filling value was defined for Abdominal Cramps so any gaps in data were just not analyzed instead of assuming zero values for those times.

Loneliness Pre-Processing

Loneliness measurement values below 1 out of 5 were assumed erroneous and removed. Loneliness measurement values above 5 out of 5 were assumed erroneous and removed. No missing data filling value was defined for Loneliness so any gaps in data were just not analyzed instead of assuming zero values for those times.

Predictive Analytics

It was assumed that 0 seconds would pass before a change in Abdominal Cramps would produce an observable change in Loneliness.

It was assumed that Abdominal Cramps could produce an observable change in Loneliness for as much as 7 days after the stimulus event.

Statistical Significance

Statistical Significance

Using a two-tailed t-test with alpha = 0.05, it was determined that the change in Loneliness is not statistically significant at a 95% confidence interval. This suggests that the Abdominal Cramps value does not have a significant influence on the Loneliness value.

After treatment, a 1.5% increase (-0.107 out of 5) from the mean baseline 2.88 out of 5 was observed. The relative standard deviation at baseline was 11.75%. The observed change was 0.25621 times the standard deviation.

A common rule of thumb considers a change greater than twice the baseline standard deviation on two separate pre-post experiments may be considered significant. This occurrence would have only a 5% likelihood of resulting from random fluctuation (a p-value < 0.05).

Data Sources

Data Sources

Abdominal Cramps data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Loneliness data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Limitations

Limitations

As with any human experiment, it was impossible to control for all potentially confounding variables. Correlation does not necessarily imply causation. We can never know for sure if one factor is definitely the cause of an outcome. However, lack of correlation definitely implies the lack of a causal relationship. Hence, we can with great confidence rule out non-existent relationships. For instance, if we discover no relationship between mood and an antidepressant this information is just as or even more valuable than the discovery that there is a relationship.

We can also take advantage of several characteristics of time series data from many subjects to infer the likelihood of a causal relationship if we do find a correlational relationship. The criteria for causation are a group of minimal conditions necessary to provide adequate evidence of a causal relationship between an incidence and a possible consequence.

Criteria For Causal Inference

Strength (A.K.A. Effect Size)

A small association does not mean that there is not a causal effect, though the larger the association, the more likely that it is causal. There is a very weakly positive (R = 0.0639) relationship between Abdominal Cramps and Loneliness.

Consistency (A.K.A. Reproducibility)

Consistent findings observed by different persons in different places with different samples strengthens the likelihood of an effect. Furthermore, in accordance with the law of large numbers (LLN), the predictive power and accuracy of these results will continually grow over time. 14 paired data points were used in this analysis. Assuming that the relationship is merely coincidental, as the participant independently modifies their Abdominal Cramps values, the observed strength of the relationship will decline until it is below the threshold of significance. To it another way, in the case that we do find a spurious correlation, suggesting that banana intake improves mood for instance, one will likely increase their banana intake. Due to the fact that this correlation is spurious, it is unlikely that you will see a continued and persistent corresponding increase in mood. So over time, the spurious correlation will naturally dissipate.

Specificity

Causation is likely if a very specific population at a specific site and disease with no other likely explanation. The more specific an association between a factor and an effect is, the bigger the probability of a causal relationship.

Temporality

The effect has to occur after the cause (and if there is an expected delay between the cause and expected effect, then the effect must occur after that delay). The confidence in a causal relationship is bolstered by the fact that time-precedence was taken into account in all calculations.

Biological Gradient

Greater exposure should generally lead to greater incidence of the effect. However, in some cases, the mere presence of the factor can trigger the effect. In other cases, an inverse proportion is observed: greater exposure leads to lower incidence.

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel.

Based on our responses so far,

0 humans feel that there is a plausible mechanism of action for a relationship between Abdominal Cramps and Loneliness.

0 humans feel that any relationship observed between Abdominal Cramps and Loneliness is coincidental.

Coherence

Coherence between epidemiological and laboratory findings increases the likelihood of an effect. It will be very enlightening to aggregate this data with the data from other participants with similar genetic, diseasomic, environmentomic, and demographic profiles.

Experiment

All of human life can be considered a natural experiment. Occasionally, it is possible to appeal to experimental evidence.

Analogy

The effect of similar factors may be considered.

Plausibility

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel. Based on our responses so far, 0 humans feel that there is a plausible mechanism of action and 0 feel that any relationship observed between Abdominal Cramps and Loneliness is coincidental.

Relationship Statistics

Property Value
Cause Variable Name Abdominal Cramps
Effect Variable Name Loneliness
Sinn Predictive Coefficient 0.011583105122498
Confidence Level LOW
Confidence Interval 0.54085
Forward Pearson Predictive Coefficient 0.0639
Critical T Value 1.771
Average Abdominal Cramps Over Previous 7 days Before ABOVE Average Loneliness 2 out of 5
Average Abdominal Cramps Over Previous 7 days Before BELOW Average Loneliness 1.89 out of 5
Duration of Action 7 days
Effect Size very weakly positive
Number of Paired Measurements 14
Optimal Pearson Product -0.0060958591588982
P Value 0.37892
Statistical Significance 0.0069
Strength of Relationship 0.54085
Study Type population
Analysis Performed At 2021-08-30
Number of Participants 2

Abdominal Cramps Info

Property Value
Variable Name Abdominal Cramps
Aggregation Method MEAN
Analysis Performed At 2020-09-23
Duration of Action 24 hours
Kurtosis 8.5536832131925
Maximum Allowed Value 5 out of 5
Mean 2.3416888888889 out of 5
Median 2.337962962963 out of 5
Minimum Allowed Value 1 out of 5
Number of Aggregate Predictors 70
Number of Aggregate Outcomes 29
Number of Measurements 99
Number of Measurements (including those generated by tagged, joined, or child variables) 99
Public true
Onset Delay 0 seconds
Standard Deviation 0.14901377231581
Unit 1 to 5 Rating
User Variables 39
UPC 753610841944
Variable Category Symptoms
Variable ID 88066
Variance 0.13522015792849

Loneliness Info

Property Value
Variable Name Loneliness
Aggregation Method MEAN
Analysis Performed At 2020-10-11
Duration of Action 24 hours
Kurtosis 1.7882861897431
Maximum Allowed Value 5 out of 5
Mean 3.1872105042017 out of 5
Median 3.1930393382353 out of 5
Minimum Allowed Value 1 out of 5
Number of Aggregate Predictors 437
Number of Aggregate Outcomes 167
Number of Measurements 3446
Number of Measurements (including those generated by tagged, joined, or child variables) 3182
Public true
Onset Delay 0 seconds
Standard Deviation 0.39907362842154
Unit 1 to 5 Rating
User Variables 404
UPC 783324854602
Variable Category Emotions
Variable ID 89438
Variance 0.44549918243977