Abstract
Attentiveness was generally 19% higher than average after a total of 28 minutes of Graphic Design Activities over the previous 7 days.
Aggregated data from 5 study participants suggests with a LOW degree of confidence (p=0.0761, 95% CI -0.612 to 0.432) that Graphic Design Activities has a very weakly negative predictive relationship (R=-0.0904) with Attentiveness.
The highest quartile of Attentiveness measurements were observed following an average 60 minutes Graphic Design Activities per day.
The lowest quartile of Attentiveness measurements were observed following an average 65 minutes of Graphic Design Activities per day.
After an onset delay of 0 seconds, Attentiveness is typically 6% lower than average over the 7 days following around 65 minutes of Graphic Design Activities Graphic Design Activities.
Keywords: Graphic Design Activities, Attentiveness, N-of-1 trials, real-world evidence, causal inference, observational study
Preliminary: Based on 5 participants. Results may change as more data is collected.
Results
Primary Findings
Analysis of 82 paired observations from 5 participants revealed a modest improvement in Attentiveness following above-average Graphic Design Activities exposure.
Supporting Statistics
What This Means
When participants had above-average Graphic Design Activities:
- Attentiveness increased by 10.7% on average
- Temporal analysis supports Graphic Design Activities as the predictor (not the outcome)
- This relationship is statistically significant (p = 0.035)
Interpreting the Predictor Impact Score
The Predictor Impact Score (PIS) integrates multiple Bradford Hill causal criteria into a single metric. Use this guide to interpret the score:
| PIS Range | Interpretation | Recommended Action |
|---|---|---|
| ≥ 0.5 | Strong evidence | High priority for RCT validation |
| 0.3 - 0.5 | Moderate evidence | Consider for experimental investigation |
| 0.1 - 0.3 | Weak evidence | Monitor for additional data |
| < 0.1 | Insufficient evidence | Low priority; may be noise |
Note: PIS is a prioritization heuristic, not proof of causation. High scores indicate relationships worth investigating, not confirmed causal effects. With only 5 participants, these scores are preliminary and will become more reliable as additional data is collected.
Optimal Daily Values
No clear dose-response relationship detected. The Graphic Design Activities values associated with high and low Attentiveness are too similar to provide meaningful dosing guidance. This may indicate a threshold effect (any amount works equally well), no effect, or insufficient data variance. With more participants, a clearer pattern may emerge.
Population Correlation
Trait Correlation Between Graphic Design Activities and Attentiveness
Graphic Design Activities Distribution
Daily Distribution
Average by Day of Week
Average by Month
Average by Year
Attentiveness Distribution
Daily Distribution
Average by Day of Week
Average by Month
Average by Year
Relationship Analysis
Attentiveness Following Graphic Design Activities
Correlation Between Graphic Design Activities and Attentiveness by Duration of Action
Correlation Between Graphic Design Activities and Attentiveness by Onset Delay
Average Graphic Design Activities Preceding Attentiveness
Average Attentiveness by Previous Graphic Design Activities
Statistical Summary
Relationship Statistics
| Property | Value |
|---|---|
| Cause Variable Name | Graphic Design Activities |
| Effect Variable Name | Attentiveness |
| Sinn Predictive Coefficient | 0.035569629501774 |
| Confidence Level | LOW |
| Confidence Interval | 0.52190349703171 |
| Forward Pearson Predictive Coefficient | -0.0904 |
| Critical T Value | 1.7454 |
| Total Graphic Design Activities Over Previous 7 days Before ABOVE Average Attentiveness | 60 minutes |
| Total Graphic Design Activities Over Previous 7 days Before BELOW Average Attentiveness | 65 minutes |
| Duration of Action | 7 days |
| Effect Size | very weakly negative |
| Number of Paired Measurements | 82 |
| Optimal Pearson Product | 0.094968927271145 |
| P Value | 0.076127578922248 |
| Statistical Significance | 0.0347 |
| Strength of Relationship | 0.52190349703171 |
| Study Type | population |
| Analysis Performed At | 2026-01-04 |
| Number of Participants | 5 |
Graphic Design Activities Info
| Property | Value |
|---|---|
| Variable Name | Graphic Design Activities |
| Aggregation Method | SUM |
| Analysis Performed At | 2020-10-11 |
| Duration of Action | 7 days |
| Filling Value | 0 |
| Kurtosis | 315.92306389138 |
| Maximum Allowed Value | 7 days |
| Mean | 5 minutes |
| Median | 576 milliseconds |
| Minimum Allowed Value | 0 seconds |
| Number of Aggregate Predictors | 13 |
| Number of Aggregate Outcomes | 139 |
| Number of Measurements | 3767 |
| Number of Measurements (including those generated by tagged, joined, or child variables) | 1538 |
| Public | true |
| Onset Delay | 0 seconds |
| Standard Deviation | 0.48081793674104 |
| Unit | Hours |
| User Variables | 46 |
| UPC | 611029338861 |
| Variable Category | Activities |
| Variable ID | 5956904 |
| Variance | 2.1027733333177 |
Attentiveness Info
| Property | Value |
|---|---|
| Variable Name | Attentiveness |
| Aggregation Method | MEAN |
| Analysis Performed At | 2020-09-17 |
| Duration of Action | 24 hours |
| Kurtosis | 2.8989604447383 |
| Maximum Allowed Value | 5 out of 5 |
| Mean | 2.6104259171135 out of 5 |
| Median | 2.603650254387 out of 5 |
| Minimum Allowed Value | 1 out of 5 |
| Number of Aggregate Predictors | 979 |
| Number of Aggregate Outcomes | 114 |
| Number of Measurements | 20541 |
| Number of Measurements (including those generated by tagged, joined, or child variables) | 20486 |
| Public | true |
| Onset Delay | 0 seconds |
| Standard Deviation | 0.46181906465469 |
| Unit | 1 to 5 Rating |
| User Variables | 1464 |
| UPC | 0 |
| Variable Category | Emotions |
| Variable ID | 1267 |
| Variance | 0.46818963151551 |
Introduction
Background
Graphic Design Activities (Activities) and Attentiveness (Emotions) are both important factors in understanding human health and well-being. This study investigates the relationship between these two variables using real-world observational data.
Traditional randomized controlled trials (RCTs), while the gold standard for causal inference, are often impractical, expensive, or unethical for studying many health relationships. Aggregated N-of-1 observational studies offer a complementary approach that leverages within-subject comparisons across large populations to identify meaningful patterns.
Research Question
Do Graphic Design Activities affect Attentiveness?
Additionally, we seek to determine:
- What is the direction and magnitude of any effect?
- How confident can we be in this relationship based on the available data?
- What are the optimal levels of Graphic Design Activities for maximizing Attentiveness?
Study Objective
The objective of this study is to determine the nature of the relationship (if any) between Graphic Design Activities and Attentiveness. Additionally, we attempt to determine the Graphic Design Activities values most likely to produce optimal Attentiveness values.
Study Overview
This is a population-level observational study using aggregated N-of-1 methodology. By aggregating individual N-of-1 experiments, we can identify population-level patterns while accounting for the substantial individual variation that exists in most health relationships. Effect sizes are reported as percent change from baseline, enabling intuitive interpretation and comparison across different measures.
Full Methodology: Framework for Real-World Evidence-Based Pharmacovigilance: Aggregated N-of-1 Trials for Quantifying Treatment Effects
Discussion
Interpretation of Findings
Participants experienced a 10.7% improvement in Attentiveness following above-average Graphic Design Activities exposure. The Predictor Impact Score (PIS) of 0.04 indicates insufficient evidence for a causal relationship. This finding is statistically significant (p = 0.035).
Statistical Significance
Using a two-tailed t-test with alpha = 0.05, it was determined that the change in Attentiveness is statistically significant at a 95% confidence interval. The p-value of 0.0347 indicates there is less than a 3.47% probability that this result occurred by chance.
After treatment, a 1.9% decrease (0.121 out of 5) from the mean baseline 2.93 out of 5 was observed. The relative standard deviation at baseline was 29.32%. The observed change was 1.06259 times the standard deviation.
A common rule of thumb considers a change greater than twice the baseline standard deviation on two separate pre-post experiments may be considered significant. This occurrence would have only a 5% likelihood of resulting from random fluctuation (a p-value < 0.05).
T-Test Details
Since t = 3.70 > 1.75, we reject the null hypothesis.
Biological Plausibility
A plausible bio-chemical mechanism between predictor and outcome is critical for interpreting observational findings. This is where human judgment excels beyond statistical analysis.
Community feedback on the biological plausibility of this relationship is still being collected. Consider the known mechanisms by which Graphic Design Activities might influence Attentiveness.
Bradford Hill Criteria Assessment
The Bradford Hill criteria provide a framework for assessing causality in observational studies. Our methodology operationalizes six of the nine criteria through the Predictor Impact Score (PIS):
| Criterion | How Addressed | Metric |
|---|---|---|
| Strength | Effect size magnitude | Percent change from baseline (Δ%), z-score |
| Consistency | Cross-participant replication | Number of users (N), number of pairs (n) |
| Temporality | Predictor precedes outcome | Temporality factor (φ), onset delay (δ > 0) |
| Biological Gradient | Dose-response relationship | Gradient coefficient (φgradient) |
| Plausibility | Biological mechanism assessment | Community votes on mechanism plausibility |
| Specificity | Category appropriateness | Interest factor (finterest) |
Predictor Impact Score (PIS)
The PIS integrates multiple Bradford Hill criteria into a composite metric quantifying how reliably a predictor affects an outcome. Higher scores indicate stronger evidence:
Population-Level PIS:
Where φ-factors are saturation functions approaching 1 as evidence accumulates:
- φusers = 1 - e-N/10 (user saturation)
- φpairs = 1 - e-n/nsig (pair saturation)
- φchange = 1 - e-Δspread/Δsig (effect spread saturation)
- w = weighted average of plausibility votes
Temporality Assessment
We assess evidence for correct causal direction using the temporality factor:
Values approaching 1 indicate the predictor precedes the outcome (supporting causation); values near 0.5 suggest ambiguous directionality; values near 0 suggest reverse causation or confounding by indication.
Limitations
As with any observational study, correlation does not prove causation. Key limitations include:
- Unmeasured confounders: Variables not tracked may influence results
- Self-selection bias: Health trackers may differ from the general population
- Measurement error: Self-reported data may contain recall bias
- Confounding by indication: Sicker individuals may use more treatments
However, within-subject comparison and temporal precedence analysis partially mitigate these limitations. If the relationship is merely coincidental, as participants independently modify their Graphic Design Activities values, the observed strength will decline over time. Spurious correlations naturally dissipate as more data is collected.
Future Directions
Future research should examine:
- Subgroup analyses to identify individual differences in response
- Potential confounders and mediators of the observed relationship
- Optimal dosing and timing for Graphic Design Activities
- Confirmation through prospective or randomized designs
- Biological mechanisms underlying the observed effects
Conclusion
📊 Preliminary Findings: With 5 participants, these results are based on limited data. Effect sizes and confidence will improve as more participants contribute data. Consider these findings directional rather than definitive.
Above-average Graphic Design Activities was associated with a 10.7% improvement in Attentiveness—a modest effect. The Predictor Impact Score of 0.04 indicates this relationship is requiring additional data before conclusions.
Bottom Line: Based on a PIS of 0.04 and a 10.7% effect size, this relationship currently lacks sufficient evidence. Continue monitoring as more data becomes available. Note: These conclusions may strengthen or change direction as more data is collected.
These findings contribute to our understanding of how Graphic Design Activities may influence Attentiveness in real-world conditions. The within-subject design and temporal analysis provide confidence in these relationships, though observational limitations remain.
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Methods
Study Design
This study is based on data donated by 5 participants. Thus, the study design is equivalent to the aggregation of 5 separate n=1 observational natural experiments.
This within-subject design is powerful because it controls for all stable individual characteristics (genetics, baseline health status, socioeconomic factors) that might otherwise confound the relationship between variables.
Data Analysis
Temporal Assumptions
The analysis incorporates temporal assumptions about the relationship between variables:
- Onset Delay: It was assumed that 0 seconds would pass before a change in Graphic Design Activities would produce an observable change in Attentiveness.
- Duration of Action: It was assumed that Graphic Design Activities could produce an observable change in Attentiveness for as much as 7 days after the stimulus event.
Statistical Methods
For each participant, we calculated the Pearson correlation coefficient between Graphic Design Activities values and subsequent Attentiveness values. Individual correlations were then aggregated using Fisher's z-transformation to produce a population-level estimate:
Individual Correlation:
Fisher's Z-Transformation:
Aggregated Correlation:
Effect Size Calculation
Effect sizes are reported as percent change from baseline. For each participant, we compare the outcome following above-average predictor values to the overall baseline outcome:
Effect Magnitude (Z-Score)
To assess effect magnitude relative to natural variability, we calculate the z-score:
where RSDbaseline is the relative standard deviation of outcome during baseline period
A z-score > 2 indicates statistical significance (p < 0.05), meaning the observed change exceeds typical baseline fluctuation and is unlikely due to random variation.
Statistical Significance
Correlation significance is assessed using a two-tailed t-test:
We reject the null hypothesis (ρ = 0) at α = 0.05 when |t| exceeds the critical value, providing statistical evidence that the observed relationship is not due to chance.
Data Sources
Graphic Design Activities data was primarily collected using RescueTime. Detailed reports show which applications and websites you spent time on. Activities are automatically grouped into pre-defined categories with built-in productivity scores covering thousands of websites and applications. You can customize categories and productivity scores to meet your needs.
Attentiveness data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.
Data Quality
Data quality measures were applied to ensure reliable results:
- Minimum Data Requirement: Only participants with sufficient paired observations were included in the analysis.
- Outlier Handling: Extreme values were winsorized to reduce the influence of measurement errors.
- Missing Data: Days with missing values were handled using appropriate filling strategies based on the variable type.
- Test User Exclusion: Test accounts and invalid users were excluded from all analyses.
Principal Investigator
Program & Methods
Cite This Study
@misc{sinn_cause_5956904_effect_1267_population_study_2026,
author = {Sinn, Mike P.},
title = {Causal Analysis: Does Graphic Design Activities Affect Attentiveness?},
year = {2026},
publisher = {The Journal of Citizen Science},
url = {https://studies.crowdsourcingcures.org/study/cause-5956904-effect-1267-population-study},
note = {Accessed: January 9, 2026}
}
Study Type: Aggregated N-of-1 Observational Mega-Study
Evidence Level: Level II (Real-World Evidence)
Methodology: Bradford Hill Criteria with Predictor Impact Score (PIS)
References
This framework was originally developed in 2013 based on the Bradford Hill criteria. Subsequent literature has independently validated similar approaches to causal inference from observational data:
- Hill, A.B. (1965). The environment and disease: association or causation? Proceedings of the Royal Society of Medicine, 58(5), 295-300. [Bradford Hill criteria]
- Lillie, E.O., et al. (2011). The n-of-1 clinical trial: the ultimate strategy for individualizing medicine? Personalized Medicine, 8(2), 161-173. [N-of-1 methodology]
- Pearl, J. (2009). Causality: Models, Reasoning, and Inference . Cambridge University Press. [Causal inference]
- Hernán, M.A., & Robins, J.M. (2020). Causal Inference: What If . Chapman & Hall/CRC. [Free textbook]
- FDA (2018). Framework for FDA's Real-World Evidence Program . U.S. Food and Drug Administration. [Regulatory context]
- Duan, N., et al. (2013). Single-patient (n-of-1) trials: a pragmatic clinical decision methodology . Journal of Clinical Epidemiology, 66(8), S21-S28.
- Platt, R., et al. (2018). The FDA Sentinel Initiative—an evolving national resource . New England Journal of Medicine, 379(22), 2091-2093.
This information is for research and educational purposes only, not medical advice. Consult a healthcare provider before making health decisions. Terms of Service