Higher Diarrhea Predicts Slightly Higher Stress for Population
Contents
Mike Sinn
PRINCIPAL INVESTIGATOR
Mike Sinn

Variables

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Diarrhea 109
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Stress 1265

Categories

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Symptoms 13336
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Emotions 2028

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Tags

Medium Confidence
Very Weak Effect Size
Positive Relationship
Population Study
cause image gauge image effect image
Participants reported a 16.3% average increase in Stress following above average Diarrhea.
Abstract

Abstract

Stress was generally 16.5% higher than average after Yes of Diarrhea per 7 days.

Aggregated data from 1 study participants suggests with a MEDIUM degree of confidence (p=0.325, 95% CI -0.195 to 0.517) that Diarrhea has a weakly positive predictive relationship (R=0.161) with Stress.

The highest quartile of Stress measurements were observed following an average Yes Diarrhea per day.

The lowest quartile of Stress measurements were observed following an average Yes of Diarrhea per day.

After an onset delay of 0 seconds, Stress is typically 2% lower than average over the 7 days following around Yes Diarrhea.

Objective

Objective

The objective of this study is to determine the nature of the relationship (if any) between Diarrhea and Stress. Additionally, we attempt to determine the Diarrhea (yes/no) values most likely to produce optimal Stress values.
Participant Instructions

Participant Instructions

Manual Recording Option

A Create a reminder for Diarrhea here and record it daily by enabling notifications or using A the reminder inbox here .


Manual Recording Option

A Create a reminder for Stress here and record it daily by enabling notifications or using A the reminder inbox here .

Design

Design

This study is based on data donated by 1 participants. Thus, the study design is equivalent to the aggregation of 1 separate n=1 observational natural experiments.

Data Analysis

Data Analysis

Diarrhea Pre-Processing

Diarrhea measurement values below No were assumed erroneous and removed. No maximum allowed measurement value was defined for Diarrhea. It was assumed that any gaps in Diarrhea data were unrecorded No measurement values.

Stress Pre-Processing

Stress measurement values below 1 out of 5 were assumed erroneous and removed. Stress measurement values above 5 out of 5 were assumed erroneous and removed. No missing data filling value was defined for Stress so any gaps in data were just not analyzed instead of assuming zero values for those times.

Predictive Analytics

It was assumed that 0 seconds would pass before a change in Diarrhea (yes/no) would produce an observable change in Stress.

It was assumed that Diarrhea (yes/no) could produce an observable change in Stress for as much as 7 days after the stimulus event.

Statistical Significance

Statistical Significance

Using a two-tailed t-test with alpha = 0.05, it was determined that the change in Stress is not statistically significant at a 95% confidence interval. This suggests that the Diarrhea value does not have a significant influence on the Stress value.

After treatment, a 16.3% increase (0.339 out of 5) from the mean baseline 2.06 out of 5 was observed. The relative standard deviation at baseline was 49%. The observed change was 0.33655 times the standard deviation.

A common rule of thumb considers a change greater than twice the baseline standard deviation on two separate pre-post experiments may be considered significant. This occurrence would have only a 5% likelihood of resulting from random fluctuation (a p-value < 0.05).

Data Sources

Data Sources

Diarrhea (yes/no) data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Stress data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Limitations

Limitations

As with any human experiment, it was impossible to control for all potentially confounding variables. Correlation does not necessarily imply causation. We can never know for sure if one factor is definitely the cause of an outcome. However, lack of correlation definitely implies the lack of a causal relationship. Hence, we can with great confidence rule out non-existent relationships. For instance, if we discover no relationship between mood and an antidepressant this information is just as or even more valuable than the discovery that there is a relationship.

We can also take advantage of several characteristics of time series data from many subjects to infer the likelihood of a causal relationship if we do find a correlational relationship. The criteria for causation are a group of minimal conditions necessary to provide adequate evidence of a causal relationship between an incidence and a possible consequence.

Criteria For Causal Inference

Strength (A.K.A. Effect Size)

A small association does not mean that there is not a causal effect, though the larger the association, the more likely that it is causal. There is a weakly positive (R = 0.161) relationship between Diarrhea and Stress.

Consistency (A.K.A. Reproducibility)

Consistent findings observed by different persons in different places with different samples strengthens the likelihood of an effect. Furthermore, in accordance with the law of large numbers (LLN), the predictive power and accuracy of these results will continually grow over time. 101 paired data points were used in this analysis. Assuming that the relationship is merely coincidental, as the participant independently modifies their Diarrhea values, the observed strength of the relationship will decline until it is below the threshold of significance. To it another way, in the case that we do find a spurious correlation, suggesting that banana intake improves mood for instance, one will likely increase their banana intake. Due to the fact that this correlation is spurious, it is unlikely that you will see a continued and persistent corresponding increase in mood. So over time, the spurious correlation will naturally dissipate.

Specificity

Causation is likely if a very specific population at a specific site and disease with no other likely explanation. The more specific an association between a factor and an effect is, the bigger the probability of a causal relationship.

Temporality

The effect has to occur after the cause (and if there is an expected delay between the cause and expected effect, then the effect must occur after that delay). The confidence in a causal relationship is bolstered by the fact that time-precedence was taken into account in all calculations.

Biological Gradient

Greater exposure should generally lead to greater incidence of the effect. However, in some cases, the mere presence of the factor can trigger the effect. In other cases, an inverse proportion is observed: greater exposure leads to lower incidence.

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel.

Based on our responses so far,

0 humans feel that there is a plausible mechanism of action for a relationship between Diarrhea and Stress.

0 humans feel that any relationship observed between Diarrhea and Stress is coincidental.

Coherence

Coherence between epidemiological and laboratory findings increases the likelihood of an effect. It will be very enlightening to aggregate this data with the data from other participants with similar genetic, diseasomic, environmentomic, and demographic profiles.

Experiment

All of human life can be considered a natural experiment. Occasionally, it is possible to appeal to experimental evidence.

Analogy

The effect of similar factors may be considered.

Plausibility

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel. Based on our responses so far, 0 humans feel that there is a plausible mechanism of action and 0 feel that any relationship observed between Diarrhea and Stress is coincidental.

Relationship Statistics

Property Value
Cause Variable Name Diarrhea
Effect Variable Name Stress
Sinn Predictive Coefficient 0.015321175548735
Confidence Level MEDIUM
Confidence Interval 0.35638
Forward Pearson Predictive Coefficient 0.161
Critical T Value 1.646
Total Diarrhea Over Previous 7 days Before ABOVE Average Stress Yes
Total Diarrhea Over Previous 7 days Before BELOW Average Stress Yes
Duration of Action 7 days
Effect Size weakly positive
Number of Paired Measurements 101
Optimal Pearson Product 0.040523014444189
P Value 0.32504
Statistical Significance 0.5906
Strength of Relationship 0.35638
Study Type population
Analysis Performed At 2021-08-30
Number of Participants 1

Diarrhea Info

Property Value
Variable Name Diarrhea (yes/no)
Aggregation Method SUM
Analysis Performed At 2020-10-11
Duration of Action 24 hours
Filling Value 0
Kurtosis 11.545691207952
Mean Yes
Median Yes
Minimum Allowed Value No
Number of Aggregate Predictors 86
Number of Aggregate Outcomes 23
Number of Measurements 154
Number of Measurements (including those generated by tagged, joined, or child variables) 154
Public true
Onset Delay 0 seconds
Standard Deviation 0.2886764558976
Unit Yes/No
User Variables 14
UPC 300450212429
Variable Category Symptoms
Variable ID 5952399
Variance 0.24317672222645

Stress Info

Property Value
Variable Name Stress
Aggregation Method MEAN
Analysis Performed At 2020-10-11
Duration of Action 24 hours
Kurtosis 1.8809357655084
Maximum Allowed Value 5 out of 5
Mean 3.1520495432579 out of 5
Median 3.1470732142857 out of 5
Minimum Allowed Value 1 out of 5
Number of Aggregate Predictors 1106
Number of Aggregate Outcomes 159
Number of Measurements 4008
Number of Measurements (including those generated by tagged, joined, or child variables) 3438
Public true
Onset Delay 0 seconds
Standard Deviation 0.37961607684605
Unit 1 to 5 Rating
User Variables 484
UPC 637769766238
Variable Category Emotions
Variable ID 1923
Variance 0.3902865870594