Higher Birth Control Predicts Very Slightly Lower Overall Mood for Population
Contents
Mike Sinn
PRINCIPAL INVESTIGATOR
Mike Sinn

Variables

A
Birth Control 108
A
Overall Mood 7137

Categories

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Treatments 9356
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Emotions 2028

Actions

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Medium Confidence
Very Weak Effect Size
Negative Relationship
Population Study
cause image gauge image effect image
Participants reported a 4.9% average decrease in Overall Mood following above average Birth Control.
Abstract

Abstract

Overall Mood was generally 2% higher than average after a total of 4.71 pills of Birth Control Pills over the previous 19 days.

Aggregated data from 7 study participants suggests with a MEDIUM degree of confidence (p=0.289, 95% CI -0.491 to 0.328) that Birth Control Pills has a very weakly negative predictive relationship (R=-0.0817) with Overall Mood.

The highest quartile of Overall Mood measurements were observed following an average 5.89 pills Birth Control Pills per day.

The lowest quartile of Overall Mood measurements were observed following an average 6.32 pills of Birth Control Pills per day.

After an onset delay of 30 minutes, Overall Mood is typically 2% lower than average over the 19 days following around 6.32 pills Birth Control Pills.

Objective

Objective

The objective of this study is to determine the nature of the relationship (if any) between Birth Control Pills and Overall Mood. Additionally, we attempt to determine the Birth Control Pills (pills) values most likely to produce optimal Overall Mood values.
Participant Instructions

Participant Instructions

Manual Recording Option

A Create a reminder for Birth Control here and record it daily by enabling notifications or using A the reminder inbox here .


Manual Recording Option

A Create a reminder for Overall Mood here and record it daily by enabling notifications or using A the reminder inbox here .

Design

Design

This study is based on data donated by 7 participants. Thus, the study design is equivalent to the aggregation of 7 separate n=1 observational natural experiments.

Data Analysis

Data Analysis

Birth Control Pre-Processing

Birth Control measurement values below 0 pills were assumed erroneous and removed. Birth Control measurement values above 20 pills were assumed erroneous and removed. It was assumed that any gaps in Birth Control data were unrecorded 0 pills measurement values.

Overall Mood Pre-Processing

Overall Mood measurement values below 1 out of 5 were assumed erroneous and removed. Overall Mood measurement values above 5 out of 5 were assumed erroneous and removed. No missing data filling value was defined for Overall Mood so any gaps in data were just not analyzed instead of assuming zero values for those times.

Predictive Analytics

It was assumed that 30 minutes would pass before a change in Birth Control Pills (pills) would produce an observable change in Overall Mood.

It was assumed that Birth Control Pills (pills) could produce an observable change in Overall Mood for as much as 19 days after the stimulus event.

Statistical Significance

Statistical Significance

Using a two-tailed t-test with alpha = 0.05, it was determined that the change in Overall Mood is not statistically significant at a 95% confidence interval. This suggests that the Birth Control Pills value does not have a significant influence on the Overall Mood value.

After treatment, a 4.9% decrease (0.006 out of 5) from the mean baseline 3.29 out of 5 was observed. The relative standard deviation at baseline was 24.029%. The observed change was 0.22368 times the standard deviation.

A common rule of thumb considers a change greater than twice the baseline standard deviation on two separate pre-post experiments may be considered significant. This occurrence would have only a 5% likelihood of resulting from random fluctuation (a p-value < 0.05).

Data Sources

Data Sources

Birth Control Pills (pills) data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Overall Mood data was primarily collected using QuantiModo. QuantiModo allows you to easily track mood, symptoms, or any outcome you want to optimize in a fraction of a second. You can also import your data from over 30 other apps and devices. QuantiModo then analyzes your data to identify which hidden factors are most likely to be influencing your mood or symptoms.

Limitations

Limitations

As with any human experiment, it was impossible to control for all potentially confounding variables. Correlation does not necessarily imply causation. We can never know for sure if one factor is definitely the cause of an outcome. However, lack of correlation definitely implies the lack of a causal relationship. Hence, we can with great confidence rule out non-existent relationships. For instance, if we discover no relationship between mood and an antidepressant this information is just as or even more valuable than the discovery that there is a relationship.

We can also take advantage of several characteristics of time series data from many subjects to infer the likelihood of a causal relationship if we do find a correlational relationship. The criteria for causation are a group of minimal conditions necessary to provide adequate evidence of a causal relationship between an incidence and a possible consequence.

Criteria For Causal Inference

Strength (A.K.A. Effect Size)

A small association does not mean that there is not a causal effect, though the larger the association, the more likely that it is causal. There is a very weakly negative (R = -0.0817) relationship between Birth Control and Overall Mood.

Consistency (A.K.A. Reproducibility)

Consistent findings observed by different persons in different places with different samples strengthens the likelihood of an effect. Furthermore, in accordance with the law of large numbers (LLN), the predictive power and accuracy of these results will continually grow over time. 102 paired data points were used in this analysis. Assuming that the relationship is merely coincidental, as the participant independently modifies their Birth Control values, the observed strength of the relationship will decline until it is below the threshold of significance. To it another way, in the case that we do find a spurious correlation, suggesting that banana intake improves mood for instance, one will likely increase their banana intake. Due to the fact that this correlation is spurious, it is unlikely that you will see a continued and persistent corresponding increase in mood. So over time, the spurious correlation will naturally dissipate.

Specificity

Causation is likely if a very specific population at a specific site and disease with no other likely explanation. The more specific an association between a factor and an effect is, the bigger the probability of a causal relationship.

Temporality

The effect has to occur after the cause (and if there is an expected delay between the cause and expected effect, then the effect must occur after that delay). The confidence in a causal relationship is bolstered by the fact that time-precedence was taken into account in all calculations.

Biological Gradient

Greater exposure should generally lead to greater incidence of the effect. However, in some cases, the mere presence of the factor can trigger the effect. In other cases, an inverse proportion is observed: greater exposure leads to lower incidence.

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel.

Based on our responses so far,

0 humans feel that there is a plausible mechanism of action for a relationship between Birth Control and Overall Mood.

0 humans feel that any relationship observed between Birth Control and Overall Mood is coincidental.

Coherence

Coherence between epidemiological and laboratory findings increases the likelihood of an effect. It will be very enlightening to aggregate this data with the data from other participants with similar genetic, diseasomic, environmentomic, and demographic profiles.

Experiment

All of human life can be considered a natural experiment. Occasionally, it is possible to appeal to experimental evidence.

Analogy

The effect of similar factors may be considered.

Plausibility

Plausibility

A plausible bio-chemical mechanism between cause and effect is critical. This is where human brains excel. Based on our responses so far, 0 humans feel that there is a plausible mechanism of action and 0 feel that any relationship observed between Birth Control and Overall Mood is coincidental.

Relationship Statistics

Property Value
Cause Variable Name Birth Control
Effect Variable Name Overall Mood
Sinn Predictive Coefficient 0.041128979263966
Confidence Level MEDIUM
Confidence Interval 0.40923
Forward Pearson Predictive Coefficient -0.0817
Critical T Value 1.678
Total Birth Control Over Previous 19 days Before ABOVE Average Overall Mood 5.89 pills
Total Birth Control Over Previous 19 days Before BELOW Average Overall Mood 6.32 pills
Duration of Action 19 days
Effect Size very weakly negative
Number of Paired Measurements 102
Optimal Pearson Product 0.047781847815214
P Value 0.28868
Statistical Significance 0.2894
Strength of Relationship 0.40923
Study Type population
Analysis Performed At 2021-08-30
Number of Participants 7

Birth Control Info

Property Value
Variable Name Birth Control Pills (pills)
Aggregation Method SUM
Analysis Performed At 2020-09-22
Duration of Action 21 days
Filling Value 0
Kurtosis 10.813340765787
Maximum Allowed Value 20 pills
Mean 0.52885951724138 pills
Median 0.46551724137931 pills
Minimum Allowed Value 0 pills
Number of Aggregate Predictors 0
Number of Aggregate Outcomes 108
Number of Measurements 262
Number of Measurements (including those generated by tagged, joined, or child variables) 261
Public true
Onset Delay 30 minutes
Standard Deviation 0.29955141863072
Unit Pills
User Variables 48
UPC 343386622306
Variable Category Treatments
Variable ID 1313751
Variance 0.17271298769136

Overall Mood Info

Property Value
Variable Name Overall Mood
Aggregation Method MEAN
Analysis Performed At 2020-09-12
Duration of Action 24 hours
Kurtosis 3.3832907631011
Maximum Allowed Value 5 out of 5
Mean 3.1202433341482 out of 5
Median 3.1415600073553 out of 5
Minimum Allowed Value 1 out of 5
Number of Aggregate Predictors 6425
Number of Aggregate Outcomes 712
Number of Measurements 617070
Number of Measurements (including those generated by tagged, joined, or child variables) 561596
Public true
Onset Delay 0 seconds
Standard Deviation 0.38176118810538
Unit 1 to 5 Rating
User Variables 9142
UPC 767674073845
Variable Category Emotions
Variable ID 1398
Variance 0.30220747449488